US scientists drive nanobots with sperm

Release date: 2008-01-10

In a groundbreaking development, U.S. scientists have successfully harnessed the power of sperm to drive nano-robots, marking a significant step forward in the field of nanotechnology. This innovation could revolutionize medical treatments by enabling precise drug delivery and targeted cellular interventions.

The research team, led by Dr. Alex Travis from Cornell University’s Department of Veterinary Medicine, has developed a bioengineered system that mimics the way sperm move through the body. By replicating the biological mechanisms that allow sperm to swim, they’ve created a miniature propulsion system for nano-robots. These tiny machines can be guided through the bloodstream to deliver medication directly to affected areas or correct enzyme deficiencies.

One of the key discoveries is how mammalian sperm generate energy. The tail, or flagellum, relies on glycolytic enzymes that convert sugar into ATP, the primary energy source for cellular functions. These enzymes are uniquely designed to attach to the rigid structure of the sperm’s tail, allowing them to efficiently produce energy for movement.

Scientists modified these enzymes so they could adhere to artificial surfaces, such as nickel-coated chips. This allows the enzymes to act as a biological engine, using glucose from the bloodstream as fuel. When properly arranged, the enzymes form a functional unit that powers the nano-robot, much like a natural motor.

This advancement opens up exciting possibilities for future medical applications. Researchers are now working on optimizing the arrangement of these enzymes to ensure they function in a coordinated manner. If successful, this technology could lead to more efficient and targeted therapies, reducing side effects and improving treatment outcomes.

As the field of nanomedicine continues to evolve, innovations like this highlight the potential of merging biology with engineering to create life-changing medical solutions. ——Shanghai Medical Device Industry Association Network

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