Aspirin helps to delay the development of chronic obstructive pulmonary disease by more than 50%
Aspirin helps to delay the development of chronic obstructive pulmonary disease by more than 50%
December 28, 2017 Source: China Circulation Author: Lu Fang
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Aspirin, the old medicine that was born in the willow bark, always gives people an unexpected surprise. This time, it is neither anti-cancer nor fertility, but studies have found that taking aspirin for 10 years regularly can delay the progression of emphysema by more than 50%.
And regardless of whether the patient smoked before, whether it is taking 81 mg or 300-325 mg of aspirin daily, regardless of whether inhaled, non-steroidal anti-inflammatory drugs, clopidogrel, statins, and diuretics are used, this benefit All in.
In particular, it is worth mentioning that it is more pronounced in older people who have significant airflow obstruction.
The investigators noted that platelet activation reduces pulmonary microvascular blood flow and promotes inflammation, while the pathogenesis of chronic obstructive pulmonary disease and emphysema is important.
"These findings further support previous animal experiments. This suggests that it is necessary to further study the association of platelet activation in patients with aspirin and emphysema," the researchers noted.
The lung study from MESA included 4,257 subjects aged 45-84 years without clinical cardiovascular disease. Of these, 54% had a history of smoking and 22% took aspirin regularly. “Regularly†is defined as taking aspirin for ≥ 3 days per week. The investigators performed spirometry and cardiopulmonary CT examinations at the beginning of the trial and 10 years later to assess the size of the emphysema area.
Source: Aaron CP, Schwartz JE, Hoffman EA, et al. A Longitudinal Cohort Study of Aspirin Use and Progression of Emphysema-like Lung on CT: The MESA Lung Study. Chest. 2017Dec 12. DOI: 10.1016/j.chest.2017.11 .031.
Original title: Old tree and new flowers: Aspirin helps to delay the development of slow-resistance lung disease by more than 50%
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