TSQ 8000 Evo GC/MS instruction manual and Thermo Fisher method package

First, TSQ 8000 Evo triple quadrupole series gas chromatography instrument

With a consistent lead in gas chromatography triple quadrupole mass spectrometry, Thermo Fisher Scientific has reinvented the TSQ 8000 after the introduction of the TSQ 8000 Evo, a highly efficient GC/MS. /MS delivers never-ending productivity with exceptional sensitivity, ultra-fast scanning speed, and easy MSMS capabilities to meet the most demanding quantitative and qualitative analysis requirements, providing the foundation for food safety, environmental analysis, forensic and pharmaceutical applications analysis.

TSQ 8000 Evo main features:
• AutoSRM function automatically optimizes secondary ion pair information;
• Timed Retention Time SRM function (T-SRM) and Timed Retention Time SIM function (T-SIM) make high-throughput detection possible, and the optimization method sets parameters without assigning time periods;
• The latest TraceFinder software, which provides the latest technology platform and user-friendly chromatographic analysis software, can directly call the database information to automatically establish data processing methods and injection methods;
• Up to 800 MRM/s scanning speed, even without extreme loss of sensitivity under extreme high-speed scanning conditions;
• Replacing the entire ion source while the mass spectrum is not venting, saving on routine system maintenance and simplifying operation;
• Double filament design with filaments on the same side;
• Double heating zone on the ion source to effectively remove the contamination of the ion source by the substrate and save maintenance time;
• Curved pre-quadpoles effectively remove neutral noise, reduce background and increase sensitivity.

Second, the method of using the package

The configuration of different instruments and different materials may be slightly different. The operation process refers to the screenshot of the following method, taking the polycyclic aromatic hydrocarbon PAH as an example:

1. Injection method use: directly use the file ending in meth in the method package , for injection analysis.


2. Data processing method establishment: directly copy the folder in the method package to C:\TraceFinderData\Methods, the method can be directly opened in TraceFinder software, this method includes data processing method and injection method.

Associate the data file completed in step 1 with the TraceFinder method to get the complete data processing method. Parameters such as retention time are changed as needed to further optimize the data processing method to obtain an accurate data processing method. No need to enter compound information, ion pair information,
Selecting the ion pair information to find the compound, all the steps are done automatically, one point, which greatly improves the analysis efficiency and simplifies the method flow.


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