Medical Network May 8th, antibiotics such as penicillin are often used to deal with bacteria, but now some bacteria are not only resistant to antibiotics, but even antibiotics. A new study uncovers the secrets of why bacteria can “eat†penicillin, and the findings help solve the problem of antibiotic contamination.
Researchers at the University of Washington Medical School in St. Louis recently published a paper in the journal Nature and Chemical Biology in the United States. They analyzed four soil bacteria that can "eat" penicillin and found three groups of genes in the process. Play an important role.
Under the action of these genes, the bacteria first release the β-lactamase, which causes the penicillin to lose its bactericidal ability, and then releases a special enzyme for decomposing penicillin into a substance that can be "edible". The whole process is like an experienced chef treating puffer fish, removing toxins first and then enjoying the food.
Penicillin is the earliest antibiotic found in humans and has played a huge role in the health field. However, as bacterial resistance increases, many antibiotics, including penicillin, become more and more limited. Recently, the speed at which humans develop new antibiotics has not kept pace with the speed at which bacteria develop resistance, which is considered a serious challenge in the global health field.
The causes of bacterial resistance include the abuse of antibiotics and the disordered discharge of pharmaceutical plants. A large number of antibiotics enter the environment such as soil and water through various means, resulting in more and more bacteria producing resistance.
Researchers say understanding how bacteria "eat" penicillin helps develop new antibiotics and helps solve antibiotic contamination problems. Because it is difficult to effectively eliminate antibiotic contamination by some bacteria naturally occurring in the environment, they believe that E. coli can be used to obtain the ability to “eat†antibiotics, and then put these bacteria where needed to help clear the soil and Antibiotic contamination in water sources.
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